The Search for a Critical Event

نویسنده

  • TIM J. CROW
چکیده

The origin of the Xq21.3/Yp regions of homology in Homo sapiens by a reduplicative translocation dated at between 3 and 2 million years BP and a subsequent (and presently undated) paracentric inversion that split the translocated block on a hominid Y short arm. Adapted from Schwartz A. et al (Reconstructing hominid Y evolution: X-homologous block, created by XY transposition, was disrupted by Yp inversion through LINE-LINE recombination. Human Molecular Genetics 1998; 7: 1-11) to show the location of the protocadherin XY gene (PCDHX and PCDHY see chapter by Sargent et al). Y

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تاریخ انتشار 2005